Lemon Balm Clinical Evidence
Can lemon balm help alleviate stress?
Lemon balm is a fragrant herb thought to have a mild sedative effect. Can it reduce acute stress?
Human clinical intervention trial
Double-blind, placebo-controlled, randomized, balanced, crossover study. Subjects took single doses of either lemon balm or a placebo on separate days, with a seven-day washout period. Their mood was assessed at baseline and 1 hour post-dose. In between, they completed a 20-minute stress-inducing test (Defined Intensity Stressor Simulation). Cognitive performance on the test was also measured.
18 healthy subjects
A single dose of 300 or 600 mg of lemon balm or placebo
In subjects taking the higher dose, lemon balm alleviated the negative mood induced by the test. These subjects’ self-ratings of calmness were significantly higher than other subjects’. Additionally, subjects taking the lower dose were significantly faster at the test, with no loss of accuracy.
These results suggest that the potential of M. officinalis to mitigate the effects of stress deserves further investigation.